Transcription of biological heart valves2 - Labcor
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biological heart valves2 - Labcor
DE GRUYTER 001 15/bmt-20 12-0148 Biomed Te c h 2013; 58(5) :389-397 Review Anatol Ciubotaru*, Serghei Cebotari, lgor Tudorac he, Erik Beckmann, Andres Hilfiker and Axel Haverich biological heart valves Abstra ct:Cardiac valvular pathologies are often caused by rheumatic fever in young adults, atherosclerosis in elderly patients, or by congenital malformation of the heart in children, in effect affecting almost all population ages. Almost 300,000 heart valve operations are performed worldwide annually. Tissue valve prostheses have certain advantages over mechanical valves such as biocompat- ibility, more physiological hemodynamics, and no need for life-long systemic anticoagulation . However, the major disadvantage of biological valves is related to their dura- bility.
390 A. Ciubotaru et al.: Biological heart valves DE GRUYTER severa! reasons. Elderly patients represent a continu ously increasing proportion of patients undergoing valve replacement. theAlso, continuous technological develop
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