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Bioreactor Design - Future is BioTechnology.

142 CHAPTER6 Bioreactor To Design a Bioreactor , some objectives have to be defined. The decisions made in thedesign of the Bioreactor might have a significant impact on overall process of reaction kinetics is essential for understanding how a biological reactorworks. Other areas of bioprocess engineering such as mass and energy balances, mixing,mass transfer and heat transfer are also Bioreactor is the heart of any biochemical process in which enzymes, microbial, mam-malian or plant cell systems are used for manufacture of a wide range of useful biologicalproducts. The performance of any Bioreactor depends on many functions, such as those listedbelow: Biomass concentration Nutrient supply Sterile conditions Product removal Effective agitations Product inhibition Heat removal Aeration Correct shear conditions Metabolisms/microbial activitiesThere are three groups of Bioreactor currently in use for industrial production:1.

Oxygen consumption High High Low Absent Mass transfer Low High Low Absent Heat production 3–15 3–15 0.03–0.14 Negligible metabolic (kW/m3) Power consumption, hp 3–15 fewer than 5 0.02–05 Negligible Ch006.qxd 10/27/2006 10:44 AM Page 143

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