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Bisocor - Square Pharmaceuticals

COMPOSITIONB isocor Tablet: Each film coated tablet contains Bisoprolol Fumarate USP 5 Tablet: Each film coated tablet contains Bisoprolol Fumarate USP 5 10 Tablet: Each film coated tablet contains Bisoprolol Fumarate USP 10 OF ACTIONB isoprolol blocks the action of the sympathetic nervous syst em on the heart by blocking the heart's beta1-adrenergic receptors. Bisoprolol reduces the heart rate & force of contr action of the heart, thus lowers blood pressure. PHARMACOKINETICSA bsorption: R apid and almost : Widely; highest concentr ations in heart, liver , lungs, and : Extensively hepatic; significant first-pass effect (~20%).Excretion: Urine (50% as unchanged drug, remainder as inactive metabolites); feces (<2%).

COMPOSITION Bisocor ® 2.5Tablet:Each film coated tablet contains Bisoprolol Fumarate USP 2.5 mg. Bisocor ® 5 Tablet:Each film coated tablet contains Bisoprolol Fumarate USP 5 mg.

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