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Bootstrap confidence intervals: when, which, what? A ...

STATISTICS IN 2000;19:1141}1164 Bootstrap con"dence intervals: when , which , what ?A practical guide for medical statisticiansJames Carpenter1,*and John Bithell21 Medical Statistics Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, of Statistics, 1 South Parks Road, Oxford, OX1 3TG, the early 1980s, a bewildering array of methods for constructing Bootstrap con"dence intervals havebeen proposed. In this article, we address the following questions. First, when should Bootstrap con"denceintervals be used.

will be adequate, where h(t) is the hazard at time t,h 0 ()) is the baseline hazard and x is an indicator covariate for treatment 2. Fitting this model gives bK"0.924 with standard error

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