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C57BL/6 Mice Datasheet - Charles River Laboratories

STEP OF THE WAYRESEARCH MODELSC57BL/6 MiceNomenclature: C57BL/6 NCrlStrain OriginDeveloped by Little in 1921 from a mating of Miss Abbie Lathrop s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory from Hall in 1948. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH. Coat ColorBlackAvailabilityNorth America, Europe, China, and JapanResearch Applications Metabolic Disease Oncology Immunology Cardiology Addiction Toxicology Transgenic Model CreationGerm-Free (GF) Axenic Free of all microorganismsVAF/Elite (SOPF) Free of all agents listed in the VAF / Plus mouse profile, plus the opportunists Beta hemolytic Streptococcus spp.

highest quality of animals. • Weekly colony health status reports available online. askcharlesriver@crl.com • www.criver.com 201 Charles River Laboratories International Inc. Research Applications and References The C57BL/6 mouse is a multipurpose model that can be used in such fields as model creation, physiology, safety and

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