Cancer Immunotherapy - MEDIAN Technologies

Cancer Immunotherapy :Criteria of Assessment with ImagingiRECIST, irRECIST, irRC, MEDIAN TechnologiesWhat is Immunotherapy ?Traditional Chemotherapies Direct killing of tumor cellsInterferes with cell division DNA damaging alkylating agents DNA intercalating agents, anthracyclines DNA synthesis-blocking antimetabolitesImmunotherapiesImmune-med iated cell killingActivates patient s immune system to detect and eliminate tumor cells Vaccines Recombinant cytokines Preformed monoclonal antibodies Immunomodulatory 2 Anti-tumor immune responseCancer-cell antigen presented on APCT cell recognition, activation, responseT cell proliferationT cell migration to tumor siteImmune-mediated tumor cell death CD8+ cytolytic T cells kill tumor cells CD4+ helper T cells secrete cytokinesT cell activation and response are regulated by a balance of stimulatory and inhibitory signals called immune checkpoints, which control the magnitude of 3 Immunotherapy treatment is a 3-step processImmunotherapy Treatm

Cancer Immunotherapy: Criteria of Assessment with Imaging iRECIST, irRECIST, irRC, RECIST1.1 mediantechnologies.com Median Technologies

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