Transcription of capto adhere dr7 - Wolfson Centre Home Page
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capto adhere dr7 - Wolfson Centre Home Page
GE Healthcare Instructions 28-9064-05 AA Multimodal media capto adhere capto adhere is a multimodal BioProcess medium for intermediate puri cation and polishing of monoclonal antibodies after capture on Protein A medium by packed bed chromatography. In combination with Protein A medium ( , MabSelect family), capto adhere offers a robust chromatography platform for the development of monoclonal antibody manufacturing processes. capto adhere improves yield, productivity and process economy with: High capacity in ow-through mode Contaminant removal to formulation levels in post Protein A puri cation: - Leached Protein A. - Antibody dimers and aggregates - Host cell proteins - Nucleic acids - Viruses Wider operational window of pH and conductivity Savings in time and operating costs with a two steps chromatographic process imagination at work Table of contents 1.
p. 6 3. Method design and optimization Capto adhere is a multimodal ion exchanger and is designed to be used as a second or third step in monoclonal antibody (MAb) purification processes,
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