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质谱技术 - CAS

2020 12 8 .. 1 . 1 . 2 . 3 . 4 . 2 . 1 ICP-MS . 2 MALDI . 3 . 4 . 5 . 6 . 7 .. (Mass Spectrometry,MS) .. , . , , . , . ( . ) .. 1886 Goldstein . 1898 Wien . 1912 Thomson , Ne . 1917 . 1918 Arthur Dempster (Electron ionization ) . 1919 Francis Aston ( 50 , ). 1934 Stephens . Herzog Hintenberger .. 1940 (Alfred Nier, father of modern mass spectrometry ) . (235U, 238U,Manhattan Project). 1942 . 1946 Stephens (Time-of flight mass analysis). 1953 Paul Steinwedel (Quadrupole analyzers). 1954 Inghram Hayden Tandem , (MS/MS). 1955 Wiley & Mclarens . 1956 Gohlke and McLafferty - (GC/MS). Beynon (High-resolution MS). 1960 (Nier) . 1965 Hipple , (Ion Cyclotron Resonance). 1966 Munson & Field (Chemical ionization ). 1967 McLafferty & Jennings, (Tandem mass spectrometry).

化学离子化Chemical Ionization (CI) 场电离, 场解吸Field Ionization (FI), Field Desorption (FD) 快原子轰击Fast Atom Bombardment (FAB) 基质辅助激光解析电离Matrix-Assisted Laser Desorption Ionization (MALDI) 电喷雾电离Electrospray Ionization (ESI) 大气压化学电离Atmospheric Pressure Chemical Ionization (APCI)

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  Assisted, Laser, Ionization, Desrotpion, Assisted laser desorption ionization

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