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Case #9: Gastroesophageal Reflux Disease

Meghan Ames Mrs. Matuszak KNH 406. February 1, 2010. Case #9: Gastroesophageal Reflux Disease Case Questions I. Understanding the Disease and Pathophysiology 1. How is acid produced and controlled within the gastrointestinal tract? Hydrochloric acid (HCl) is released from parietal cells in the stomach lining in response to histamine, gastrin, and acetyl choline (ACh). Somatostatin inhibits histamine, and thus secretion of HCl when pH falls. HCl is secreted during the cephalic and gastric phases of digestion.

Meghan Ames Mrs. Matuszak KNH 406 February 1, 2010 Case #9: Gastroesophageal Reflux Disease Case Questions I. Understanding the Disease and Pathophysiology

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