Transcription of 腸病毒感染及其併發症 - ccd.org.tw
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腸病毒感染及其併發症 - ccd.org.tw
(Enterovirus). Picornaviridae (pico= ; rna=RNA). 30 nm . RNA (+).. (50oC 1 hr). ( ) ( ) ( ppm). (Enterovirus): 67 . : . (coxsackievirus). A : 1-24 (A23 ) 23 . B : 1-6 6 . (echovirus). 1-34 (8,10,28 ) 31 . enteric cytopathogenic human orphan virus (newer enteroviruses). 68, 69, 70, 71.. : . : .. NTUH Experience: Year 1998. 1871 outpatients: hand-foot-mouth disease or herpangina Male/female= 900. 800. <12 M/O 700. 600. 1-4 Y/O 500. 400. 300. 5-14 Y/O 200. 100. >15 Y/O 0. Nov Jun Aug Jul Jan Sep Dec Feb Apr May Mar Oct Number of cases and outcome of severe HFMD and herpangina in Taiwan, 1998. Ho, M. et al., N Engl J Med 1999;341:929-35. Liu CC, et al., J Clin Virol 2000;17:23-30.. 40-90%.. 70 .. : . : . (minor viremia).. (major viremia).. : 2-3 (1-35 ). : -3 -- 35 .. : .. : . ( ). (meningeal sign). : .. : . ( ). (meningeal sign).. : .. 1-2 .. X : .. : . : . 1/5 -- 2/3. B (B1-B4) 11 . Enterovirus: Neonatal infection Most vulnerable age for severe infection 666 neonates culture at 24 hr, 1 wk, 2 wk, 3 wk, 1 mo nonpolio infection risk factors lower socioeconomic status lack of breast-feeding 50/100,000 coxsackie B.
腸病毒(Enterovirus) • 屬於Picornaviridae (pico=小; rna=RNA) • 無外套、正二十面體、直徑30 nm 、內含一條 單股RNA (+) • 下列可殺死病毒
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