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CDC Guideline for Prescribing Opioids for Chronic Pain ...

CDC Guideline for Prescribing Opioids for Chronic Pain United States, 2016. morphine milligram equivalent (MME) doses for commonly prescribed Opioids opioid Conversion Factor Codeine Fentanyl transdermal (in mcg/hr). Hydrocodone 1. Hydromorphone 4. 1 20 mg/day 4. 21 40 mg/day 8. 41 60 mg/day 10. 61 80 mg/day 12. morphine 1. Oxycodone Oxymorphone 3. Tapentadol Clinicians should use caution when Prescribing Opioids at any dosage, should carefully reassess evidence of individual benefits and risks when increasing dosage to 50 morphine milligram equivalents (MME)/day, and should avoid increasing dosage to 90 MME/day or carefully justify a decision to titrate dosage to 90 MME/day Source: Adapted from Von Korff M, Saunders K, Ray GT, et al. Clin J Pain 2008;24:521 7 and Washington State Interagency Guideline on Prescribing Opioids for Pain ( ).

Clinicians should use caution when prescribing opioids at any dosage, should carefully reassess evidence of individual benefits and risks when increasing dosage to ≥50 morphine milligram equivalents (MME)/day, and should avoid

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