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Cell Communication - Yale University

Cell CommunicationPeter TakizawaDepartment of Cell Biology1. Enormously Focus on the Don t try to remember name of every Have taken out names in most figures, where names are listed, probably important. General principles of signaling Why is signaling so complicated? Signaling through steroids and ion channels Cellular signal processingCells communicate to elicit responses and coordinate , Saturday night?Nah, gotta studythe TCA and interpretationResponseCells communicate to change in behavior in one cell and coordinate activities. The language of cells consists of small molecules Receptors in cells detect small molecules and connections between receptors and cellular machinery interpret the signals.

Proteins in the cell membranes of di!erent cells can bind each other and the interaction between these proteins can alter cell behavior. For example, a T-cell uses its receptor to recognize antigen on the surface of antigen presenting cell. Another form of this type of signaling is the communication between neurons and their target cells.

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Blood vessels: the endothelium - Yale University

medcell.med.yale.edu

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