Transcription of Chapter 11 Downstream Processing - Biomanufacturing
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Chapter 11 Downstream Processing - Biomanufacturing
Chapter 11 Downstream Processing 424 Downstream Processing Objectives This Chapter provides an overview of Downstream Processing . After completing this Chapter , students will be able to: describe the general elements of the Downstream purification process for a typical monoclonal antibody-based therapeutic, starting with the bioreactor harvest pool and finishing with pre-formulation, pure drug product. explain the overall goals of the purification process from the standpoint of purity, yield, and efficiency as well as the general strategies employed to achieve these goals.
This chapter provides an overview of downstream processing. After completing this chapter, students will be able to: describe the general elements of the downstream purification process for a typical monoclonal antibody-based therapeutic, starting with the bioreactor harvest pool and finishing with pre-formulation, pure drug product.
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