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CHAPTER4

*CHAPTER 4 Pathophysiologyand differential diagnosisof anaemiaJean-Fran ois Lambert, Photis (108-141):EBMT2008 4-12-2009 16:05 Pagina 1081. Definition and classification of anaemiasAnaemia is a common condition, particularly in young women and in the geriatricpopulation, and is a significant public health problem in developing is defined by the World Health Organisation as haemoglobin (Hb) < 120g/L in women and Hb < 130 g/L in men. This definition also includes the so-calledpseudo anaemic states (pregnancy, cardiac heart failure and hyperproteinaemia) whereHb concentration falls as the result of an increase of the plasma volume.

depletionandofchronicgastritis(6-8). Progressinourknowledgeaboutironmetabolismhasledtotherecognitionofthe hereditary forms of iron deficiency anaemias.

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