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CITF MONTLY REVIE

CITF MONTHLYREVIEWV accine effectiveness against OmicronReviewing what we know about long COVIDA nswers about boosters, rapid antigen tests and more!FEBRUARY2022 Omicron variant 363 XThe number of mutations in the spike protein Omicron harbours compared to the original strain. Original SARS-CoV-2 Since its emergence in 2019, the SARS-CoV-2 virus has spread through billions of people, allowing it to evolve to be fitter. Variants that perform better will quickly outcompete other strains to become the dominant strain. VS. Number of spike protein mutations in variantsBetaGammaOmicronAlphaDeltaThe substantial number of new mutations in Omicron s genetic makeup has enabled it to behave and look very differently from the original strain of SARS-CoV-2 as well as the other variants of concern.

A booster was found to give excellent protection against hospitalization and death, whether the infection was due to Delta or Omicron. VE against symptomatic infection from Delta was good 8 months after a 2nd dose and any lost VE was restored 7 days after a booster. Protection against symptomatic infection from Omicron was lower than against ...

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