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「代謝性アシドーシスを伴うCKD患者への 重曹投与は

jhospitalist network CKD . CKD . Bicarbonate Supplementation Slows Progression of CKD. and Improves Nutritional Status 2016 5 2 .. 80 . 10 . K ) . ARB eGFR .. 2 . CKD). 5mg 15mg 1mg . 155cm 58kg 150/86mmHg 60bpm . III IV . fine crackles wheeze .. WBC 6500/ l Hb Plt 24 / l BUN 28mg/dl Cr eGFR 25. Na139mmol/l K Cl 111mmol/l HCO3- 18mmol/l glucose 180mg/dl HbA1C Xp .. CKD .. EBM 5 steps Step1 PICO . Step2 . Step3 . Step4 . Step5 Step1-4 . EBM 5 steps Step1 PICO . Step2 . Step3 . Step4 . Step5 Step1-4 . Step1 PICO. Patient .. CKD . Intervention NaHCO3) . Comparison . Outcome .. EBM 5 steps Step1 PICO . Step2 . Step3 . Step4 . Step5 Step1-4 . Step2 . UpToDate CKD .. Pathogenesis, consequences, and treatment of metabolic acidosis in chronic kidney disease . TREATMENT OF METABOLIC ACIDOSIS IN CKD . Evidence supporting bicarbonate therapy - Slowing of CKD progression . J Am Soc Nephrol. 2009 Sep;20(9):2075-84. PMID: 19608703.. EBM 5 steps Step1 PICO.

JHOSPITALIST network 「代謝性アシドーシスを伴うCKD患者への 重曹投与はCKD進行を抑制するか」 Bicarbonate Supplementation Slows Progression of CKD and Improves Nutritional Status 2016年5月2日 神戸大学医学部附属病院総合内科 担当者 南地克洋 監修 森 寛行

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