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CMS Manual System

CMS Manual System Department of Health & Human Services (DHHS) Pub 100-04 Medicare Claims Processing Centers for Medicare & Medicaid Services (CMS) Transmittal 1412 Date: JANUARY 11, 2008 Change Request 5699 Subject: Reporting of Hematocrit or Hemoglobin Levels on All Claims for the Administration of Erythropoiesis stimulating Agents (ESAs), Implementation of New Modifiers for Non-ESRD Indications, and Reporting of Hematocrit/Hemoglobin Levels on all Non-ESRD, Non-ESA Claims Requesting Payment for Anti-Anemia Drugs I. SUMMARY OF CHANGES: Effective for all claims requesting payment for the administration of ESAs with dates of service on and after January 1, 2008, CMS, in conjunction with section 110 of Division B of the Tax Relief and Health Care Act legislation of 2006, will require that the most recent hematocrit and/or hemoglob

A. Background: The treatment of anemia in cancer patients includes the use of erythropoiesis stimulating agents (ESAs) such as recombinant erythropoietin and darbepoetin. Though other pharmacologic interventions are possible, ESAs are commonly prescribed. Recently published data regarding the use of ESAs have raised safety concerns.

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