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P 1 Considerations when using LC-MS/MS Systems with Fast and high resolution liquid chromatography Mark Kuracina and Andr Schreiber AB SCIEX Concord, Ontario (Canada) Overview This application note describes the benefits of using Fast and high resolution HPLC Systems with small particle size columns and mass spectrometric detection. Requirements for HPLC and MS/MS Systems are discussed to enable quantitation with highest throughput, sensitivity and/or resolution . Introduction The advent of small particle size high Performance liquid chromatography (HPLC) columns has caused a renewed focus on the front end separation technology leading into Mass Spectrometry (MS) Systems .
p 1 Considerations when using LC-MS/MS Systems with Fast and High Resolution Liquid Chromatography Mark Kuracina and André Schreiber AB …
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