Transcription of CORTICOSTEROID INDUCED AVASCULAR …
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CHAPTER 35 INTRODUCTIONAva scu lar nec ro si s (AVN) is a pr oc ess that is du e to thete mp ora ry o r p er manent loss o f th e bloo d sup pl y to anarea of b on e. As a resul t, the bone ti ssue di es a nd the bonecol la ps es . If t he AV N involves a j oint , it can lead to destru ction of cartilage, re sulting in arth ritis and N c an be classi fi ed into 2 g ene ral c ategor ies , trau mati c and non traum ati c. I n the case of trau ma , a fract uredis rupts the blood supply to the bone leadi ng t o AVN. In the ca se of nont raumatic AVN, some ot her path ol ogy dis rupts the blood vessels. Thes e i nc lude idiopat hi c (n o ca use is ev er f ound), steroi ds ( ., anabolic a nd h igh dose- cor tic oste roids [pred nis one ] g ive n for rheuma toidar thr it is, lupus, or cancer), excess al cohol consumpt ion ,sic kl e ce ll an emia, or rad iatio n t reat ments (1 ).
C H A P T E R 35 INTRODUCTION Avascular necrosis (AVN) is a process that is due to the temporary or permanent loss of the blood supply to an area of bone.
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