Crosslinking Effect on Polydimethylsiloxane Elastic ...

Crosslinking Effect on Polydimethylsiloxane Elastic Modulus Measuredby Custom-Built Compression InstrumentZhixin Wang, Alex A. Volinsky, Nathan D. GallantDepartment of Mechanical Engineering, University of South Florida, Tampa, Florida 33620 Correspondence to: A. A. Volinsky (E-mail: macroscopic compression test utilizing a simple custom-built instrument was employed to measure polydimethylsilox-ane (PDMS) Elastic modulus. PDMS samples with varying Crosslinking density were prepared with the elastomer base to the curingagent ratio ranging from 5 : 1 to 33 : 1. The PDMS network Elastic modulus varied linearly with the amount of crosslinker, rangingfrom MPa to MPa for the samples tested. PDMS Elastic modulus in MPa can be expressed as 20 MPa/PDMS base to curingagent ratio. This article describes a simple method for measuring Elastic properties of soft polymeric Wiley Periodicals,Inc. J. Appl. Polym. ,131, : Crosslinking ; mechanical properties; properties and characterizationReceived 22 April 2014; accepted 22 May 2014 DOI: (PDMS) is one of the most widely usedsilicone-based organic can be used as thesubstrate to grow mammalian cells, including stem cells,because of its controllable range of Elastic 4 Varyingthe degree of Crosslinking in the polymer network allows tuningits mechanical properties in a range similar to the living lower the degree of PDMS network s crossli)

its stiffness.5 Conversely, the higher the degree of crosslinking, the stiffer the sample will be. To study the PDMS network stiff-ness effect on the growth and behavior of cells, one would need to characterize the mechanical properties of a series of PDMS network samples cured to different crosslink densities.

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