Transcription of Data Sheet ABILIFYTM - Medsafe
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August2016 - 1 - data Sheet for ABILIFYTM aripiprazole Tablets: 5 mg 10 mg, 15 mg, 20 mg & 30 mg NAME OF THE MEDICINE Aripiprazole. Aripiprazole is 7-[4-[4-(2, 3-dichlorophenyl)-1-piperazinyl] butoxy]-3, 4- dihydrocarbostyril. DESCRIPTION ABILIFYTM is a novel antipsychotic agent with unique pharmacologic properties and a chemical structure that differs from current antipsychotic agents. The empirical formula is C23H27Cl2N3O2 and its molecular weight is The chemical structure is: The CAS registry number for aripiprazole is 129722-12-9. Since aripiprazole is insoluble in water with its equilibrium solubility being about w/v, its pKa was established in 20% aqueous ethanol pKa = (20% ethanol, at 25 C).
NZ_DS_Abilify_V2.1_ August2016 - 2 - PHARMACOLOGY Pharmacodynamics The mechanism of action of ABILIFYTM, as well as other drugs having efficacy in schizophrenia and bipolar disorder, is unknown. However, it has been proposed that the efficacy of ABILIFYTM is mediated through a combination of partial agonist activity at …
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