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DELETION INSERTION FRAMESHIFT POINT MUTATION …

Name: _____ BIO300/CMPSC300 MUTATION - Spring 2016 As you know from lecture, there are several types of MUTATION : DELETION (a base is lost) INSERTION (an extra base is inserted) DELETION and INSERTION may cause what s called a FRAMESHIFT , meaning the reading frame changes, changing the amino acid sequence. POINT MUTATION (one base is substituted for another) If a POINT MUTATION changes the amino acid, it s called a MISSENSE MUTATION . If a POINT MUTATION does not change the amino acid, it s called a SILENT MUTATION .

2. Name one amino acid that has more than one codon. Name one amino acid that has only one codon. 3. Look at the following sequence: THE FAT CAT ATE THE RAT. Delete the first “H” and regroup the letters in groups of three. Write out the new groups of three. Does the sentence still make sense? What type of mutation is this an example of? 4.

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