Transcription of DETAILED STATISTICAL ANALYSIS PLAN (SAP)
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DETAILED STATISTICAL ANALYSIS PLAN (SAP)
STATISTICAL ANALYSIS plan Simple Intensive Care Studies-I 1 DETAILED STATISTICAL ANALYSIS PLAN (SAP) 1. Administrative information Title, registration, versions and revisions Full study title A prospective observational study on the value of conventional hemodynamic parameters in estimating cardiac output and predicting mortality in critically ill patients Acronym Simple Intensive Care Studies-I (SICS-I) Local project number 201500144 number NCT02912624 Study protocol version (23 September 2016) SAP version (3 April 2018) SAP revision history None SAP revision justification - SAP revision timing Revision will be conducted after publishing the two main manuscripts. This revision will concern DETAILED SAPs for each sub-study. STATISTICAL ANALYSIS plan Simple Intensive Care Studies-I 2 Roles and responsibility Author Bart Hiemstra1 Statistician Ilja M. Nolte2 Principle investigator Iwan van der Horst1 Contributors and roles Pim van der Harst3: revised the SAP Frederik Keus1: contributed to the design and revised the SAP Harold Snieder2: revised the SAP Chris HL Tio2: main contributor to the section missing data Jos N Alves Castela Cardoso Forte1: drafted the section additional analyses: machine learning J rn Wetterslev4: contributed to the design and revised the SAP.
Statistical analysis plan Simple Intensive Care Studies-I . 1 . DETAILED STATISTICAL ANALYSIS PLAN (SAP) 1. Administrative information 1.1. Title, registration, versions and revisions Full study title A prospective observational study on the value of conventional hemodynamic parameters in estimating cardiac output and predicting
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