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Diabetic ketoacidosis and hyperosmolar hyperglycemic ...

For personal use only 1 of 15 Sources and section criteriaWe searched PubMed from May 1975 through January 2019 to identify English language articles published in peer reviewed journals by using the following search terms: Diabetic ketoacidosis , euglycemic Diabetic ketoac-idosis, hyperosmolar hyperglycemic syndrome, hyper-glycemic crisis, sodium glucose cotransporter 2 (SGLT2) inhibitors, protocols, cerebral edema, and hyperchlo-remic metabolic acidosis. We also identified references from relevant review articles, as well as from the similar items section of PubMed. We screened and reviewed more than 200 articles in the preparation of this manuscript. We reviewed only articles including humans. We consid-ered inclusion of studies with smaller numbers of par-ticipants to be important, as these make up the majority of prospective studies for both Diabetic ketoacidosis and HHS.

hyperglycemia, high serum osmolality, and dehydra-tion (table 2). 4 8. The presentation of each of these dia-betic emergencies often overlaps. 3 8. Early diagnosis and management with attention to prevention strategies are essential to improve patients’ outcomes. 1 2. This is particu - larly important for patients presenting with “euglycemic”

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  Management, Hyperglycemia

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