Transcription of DLCO: Diffusion lung capacity for Carbon Monoxide
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DLCO: Diffusion lung capacity for Carbon Monoxide
DLCO: Diffusion lung capacity for Carbon Monoxide What is DLCO? The DLCO measures the ability of the lungs to transfer gas from inhaled air to the red blood cells in pulmonary capillaries Diffusing capacity is intended to provide an estimate of the rate at which test molecules move by Diffusion from alveolar gas to pulmonary capillary blood flow. Lung Function: Physiology, Measurement and Application in Medicine 2006 by John E. Cotes What's in the name? Diffusing capacity is an earlier name for transfer factor, still used in many centers. It is inappropriate for two reasons It is usually obtained at rest when the index is submaximal so it is not a capacity measurement Several processes contribute to the rate constant, not only Diffusion Lung Function: Physiology, Measurement and Application in Medicine 2006 by John E. Cotes Why CO and not O2/Nitric Oxide? Oxyhemoglobin dissociates readily so there is a material back tension of oxygen in the plasma CO is not normally present in body thereby causing practically no back tension.
What is DLCO? •The DLCO measures the ability of the lungs to transfer gas from inhaled air to the red blood cells in pulmonary capillaries •Diffusing capacity is intended to provide an estimate of the rate at
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