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Draft PRODUCT INFORMATION - Medsafe

140416 NEXAVAR data sheet Page 1 of 25 Data Sheet N E X AVA R sorafenib tosylate Tablets, film-coated 200 mg name of the Medicine NEXAVAR is a multikinase inhibitor targeting several serine/threonine and receptor tyrosine kinases. sorafenib tosylate is 4-(4-{3-[4-Chloro-3- (trifluoromethyl)phenyl]-ureido}phenoxy) -N2-methylpyridine-2- carboxamide 4-methylbenzenesulfonate. The empirical formula is C21H16 ClF3N4O3 x C7H8O3S and the CAS number is 28844-1- 73-01 ( sorafenib ) and 475207-59-1 ( sorafenib tosylate). sorafenib tosylate has the following structural formula: NHNHOONNHCH3 OClFFFCH3 SOOHO Description sorafenib tosylate is a white to yellowish or brownish solid with a molecular weight of 637 g/mol.

140416 NEXAVAR data sheet Page 1 of 25 Data Sheet . NEXAVAR ® Sorafenib tosylate Tablets, film-coated 200 mg . Name of the Medicine . NEXAVAR is a multikinase inhibitor targeting several serine/threonine and receptor

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