Transcription of Drug-induced peptic ulcer disease - mcppnet.org
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Issue 10 Summer 2005 Journal of the Malta College of Pharmacy Practice 15 IntroductionFollowing the discovery of theassociation of peptic ulcer disease withHelicobacter pylori infection there has beena decline in the prevalence ofuncomplicated peptic ulcer disease . Incontrast, a striking rise in admissions forulcer haemorrhage and perforation amongelderly people is now being observed. Thisrise has been attributed to the increaseduse of non-steroidal anti-inflammatorydrugs (NSAIDs) and low-dose Drug-induced peptic ulcers are not exclusive toanti-inflammatory drugs, other medicinessuch as bisphosphonates, potassiumDrug- induced pepticulcer diseaseClinical Pharmacist, St Luke s Hospital, Guardamangia, MaltaEmail: words: peptic ulcer , medicines, prostaglandins, gastrointestinal protection,gastrointestinal toxicityFor more than a century, peptic ulcer disease has been amajor cause of morbidity and peptic ulcer diseaseis a heterogeneous group of disorders involving thegastrointestinal tract and results from an imbalance betweenthe aggressive forces of gastric acid and pepsin and thedefensive mechanisms of the gastric ,2,3supplements, cortico
Issue 10 Summer 2005 Journal of the Malta College of Pharmacy Practice 15 Introduction Following the discovery of the association of peptic ulcer disease with ...
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