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Effectsofcaffeineonhumanhealth - Community …

Food Additives and Contaminants, 2003, Vol. 20, No. 1, 1 30. E ects of ca eine on human health P. Nawrot*, S. Jordan, J. Eastwood, J. Rotstein, A. tal malformations, development, fertility, foetal Hugenholtz and M. Feeley growth, pregnancy, spontaneous abortion, tea Toxicological Evaluation Section, Chemical health Hazard Assess- ment Division, Bureau of Chemical Safety, Food Directorate, health Canada, Tunney's Pasture, PL 2204D1, Ottawa, Ontario, Canada K1A 0L2 Introduction (Received 19 November 2001; revised 17 June 2002; accepted Ca eine (1,3,7-trimethylxanthine) is a natural alka- 18 June 2002). loid found in co ee beans, tea leaves, cocoa beans, cola nuts and other plants. It is probably the most Ca eine is probably the most frequently ingested frequently ingested pharmacologically active sub- pharmacologically active substance in the world.

Effectsofcaffeineonhumanhealth P.Nawrot*,S.Jordan,J.Eastwood,J.Rotstein,A. Hugenholtz and M. Feeley Toxicological Evaluation Section, Chemical Health

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