EASL Clinical Practice Guidelines: The diagnosis and ...
Primary biliary cholangitis (PBC; formerly known as primary bil-iary cirrhosis [1]) is an important but uncommon disease that predominantly affects women. It is a globally recognised autoim-mune cholestatic liver disease [2–5] with several characteristics, including: cholestasis, serologic reactivity to antimitochondrial
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EASL Clinical Practice Guidelines: Management of ...
easl.euof hepatocellular carcinomaq European Association for the Study of the Liver⇑ Summary Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-related death globally. Hepato-cellular carcinoma represents about 90% of primary liver can-cers and constitutes a major global health problem. The
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EASL Clinical Practice Guidelines: Autoimmune hepatitisq
easl.euAutoimmune hepatitis (AIH) was the first liver disease for which an effective therapeutic intervention, corticosteroid treatment, was convincingly demonstrated in controlled clinical trials. However, 50 years later AIH still remains a major diagnostic and therapeutic challenge. There are two major reasons for this
EASL recommendations on treatment of hepatitis C: Final ...
easl.euEuropean Association for the Study of the Liver* Summary Hepatitis C virus (HCV) infection is a major cause of chronic liver ... fibrosis and cirrhosis with or without hepatocellular carcinoma (HCC). Clinical care for patients with HCV-related liver disease has advanced considerably during the last couple of decades,
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EASL Clinical Practice Guidelines for the management of ...
easl.euq Clinical Practice Guideline Panel: Paolo Angeli (Chair), Mauro Bernardi ... patients with bacterial infections are burdened by severe mor-bidity,uptoACLF, andhigh mortality.6,7 Because ofthese events, decompensation represents a prognostic watershed, as the med-
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EASL clinical practice guidelines on the management of ...
easl.euto increased proximal as well as distal tubular sodium reab-sorption rather than to a decrease of filtered sodium load [19,20]. The mediators of the enhanced proximal tubular reab-sorption of sodium have not been elucidated completely, while the increased reabsorption of sodium along the distal tubule is mostly related to hyperaldosteronism [21].
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EASL Clinical Practice Guidelines on the management of ...
easl.euThe evidence and recommendations in these guidelines have been graded according to the grading of the recommendations assessment development and evaluation (GRADE) system [2]. The strength of recommendations reflects the quality of underly-ing evidence. The GRADE system offers two grades of recommen-dation: strong (1) or weak (2) (Table 1).
Guidelines, Practices, Management, Seal, Clinical, Recommendations, Easl clinical practice guidelines on the management
EASL Clinical Practice Guidelines: Management of alcohol ...
easl.eusure form provided by the EASL Office prior to work commenc-ing. The EASL Ethics Committee reviewed the composition of the panel to eliminate the potential for real or perceived bias. The CPG panel conflict of interests are declared in this submission. Methods These guidelines have been produced using evidence published before 1 October, 2017.
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EASL Clinical Practice Guidelines on nutrition in chronic ...
easl.euprognosis of patients with liver cirrhosis.13–15,3 No previous guidelines released by the European Association for the Study of Liver Disease (EASL) have dealt with nutrition in …
EASL Clinical Practice Guidelines: Drug-induced liver injury
easl.euaetiologies of liver disease. Idiosyncratic hepatotoxicity can be severe, leading to a particularly serious variety of acute liver ... US,17,18 Europe19,20 and Japan.21 In the US and Europe, idiosyn-cratic drug reactions due to conventional medications are the ... The burden of herbal and complementary medicines hepatotoxicity
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EASL Clinical Practical Guidelines on the management of ...
easl.euliver disease in the context of appropriate abnormalities in liver blood tests and coagulation profile (evidence level II-2, grade of recommendation 1). The clinical appearance of hepatic encephalopathy is cru-cial for the diagnosis of ALF but mental alterations may be initially subtle and intensive screening at the first sign
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Primary Biliary Cholangitis: 2018 Practice Guidance from ...
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