Transcription of ECTODERM: NEURULATION, NEURAL TUBE, …
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ECTODERM: NEURULATION, NEURAL TUBE, …
Taube P. RothmanP&S Reading: Larsen Human Embryology, 3rd Edition, pp. 85-102, 126-130 Summary:In this lecture, we will first consider the induction of the NEURAL plate and the formation of the neuraltube, the rudiment of the central nervous system (CNS). The anterior portion of the NEURAL tube givesrise to the brain, the more caudal portion gives rise to the spinal cord. We will see how the requisitenumbers of NEURAL progenitors are generated in the CNS and when these cells become post mitotic. Themolecular signals required for their survival and further development will also be discussed. We willthen turn our attention to the NEURAL crest, a transient structure that develops at the site where the neuraltube and future epidermis meet.
4-3 At the tissue level, neurulation occurs in four stages (Figure 4-2): (i) transformation of the central portion of the embryonic ectoderm into a thickened neural plate (ii) shaping and elongation of the
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