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Edema: Diagnosis and Management - American Academy of ...

102 American Family Physician Volume 88, Number 2 July 15, 2013 Edema: Diagnosis and ManagementKATHRYN P. TRAYES, MD, and JAMES S. STUDDIFORD, MD, Thomas Jefferson University Hospital, Philadelphia, PennsylvaniaSARAH PICKLE, MD, Rutgers Robert Wood Johnson Medical School, New Brunswick, New JerseyAMBER S. TULLY, MD, Cleveland Clinic, Cleveland, Ohio Edema is an accumulation of fluid in the intercellular tissue that results from an abnormal expansion in interstitial fluid volume. The fluid between the interstitial and intravascular spaces is regulated by the capillary hydro-static pressure gradient and the oncotic pressure gradient across the The accumulation of fluid occurs when local or systemic conditions disrupt this equilib-rium (Ta b l e 11-13), leading to increased capil-lary hydrostatic pressure, increased plasma volume, decreased plasma oncotic pressure (hypoalbuminemia), increased

Jul 15, 2013 · Edema is an accumulation of fluid in the interstitial space that occurs as the capillary filtration exceeds the limits of ... hypertension if suggested

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