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Electrocardiographic Changes in Infectious Diseases

Hospital Physician September 2007 15 Electrocardiography is a valuable, noninvasive graphical representation of the heart s electri-cal activity. Augustus D. Waller, a physiologist from London, published a description of the first human electrocardiogram (ECG) in 1887,1 and since then, the ECG has evolved as a useful tool in diagnosing coronary artery disease, rhythm abnormali-ties, and certain medical conditions. In addition, the ECG can play an important role in the assessment of the severity of illness in a variety of infections and may at times serve as a marker of cardiac involvement or cardiac complications from infection and provide information on The ECG manifestations of infections are oftentimes insignificant but can rep-resent a life-threatening complication, such as para-aortic valve abscess in endocarditis. ECG abnormalities in infections can be caused by multiple factors, includ-ing direct invasion by the microorganism, the effects of the organism s toxin, and electrolyte, metabolic, or autonomic system abnormalities caused by the infec-tion.

www.turner-white.com Hospital Physician September 2007 17 N a l m a s e t a l : E l e c t r o c a r d i o g r a p h i c C h a n g e s : p p . 1 5 – 2 7

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