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ENDOCRINE TEST PROTOCOLS - BC Children’s

July 24, 2018 Page 1 of 24 MEDICAL INVESTIGATION FACILITY ENDOCRINOLOGY & DIABETES UNIT ENDOCRINE TEST PROTOCOLS July 24, 2018 Page 2 of 24 ACTH STIMULATION TEST ..3 COSYNTROPIN 1 g/mL INJECTION ..4 oCRH STIMULATION TEST ..5 GROWTH HORMONE STIMULATION TESTS ..6 ARGININE ..6 GLUCAGON ..7 CLONIDINE ..7 INSULIN ..8 TRH STIMULATION TEST ..9 GnRH STIMULATION TEST .. 10 GLUCOSE TOLERANCE TEST FOR DIABETES ORAL .. 11 GLUCOSE TOLERANCE TEST IV .. 12 PROLONGED FAST FOR EVALUATION OF HYPOGLYCEMIA .. 13 GLUCAGON STIMULATION TEST FOR HYPOGLYCEMIA .. 15 GROWTH HORMONE SUPPRESSION TEST .. 16 CALCIUM PENTAGASTRIN STIMULATION TEST .. 17 WATER DEPRIVATION TEST .. 19 HYPERTONIC SALINE INFUSION TEST .. 20 APPENDICES .. 21 July 24, 2018 Page 3 of 24 ACTH STIMULATION TEST PURPOSE: The rapid ACTH stimulation test measures the adrenal response to ACTH and is used to diagnose primary and secondary adrenal insufficiency and defects of adrenal hormone synthesis.

response to oCRH and is used to diagnose Cushing syndrome. It is often performed 2 h after the end (i.e. at 0800 h) of a 48-h low-dose dexamethasone suppression test to rule out Cushing syndrome. PREPARATION: Patient should be fasting. No recent recently administered (within 24 h) radioisotope scan.

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