EPP - 日本対がん協会

H23 010. RCU . 1.. 3 . - 23 7 18 5 .. - 1 23 8 5 10 .. - 2 23 9 30 25 .. 1) .. 18 22 .. (CDDP) (PEM) . (extrapleural pneumonectomy: EPP) . (feasibility study) . (JMRC-01 ) JMRC-01 . 42 22 11 . EPP (30/42) . (4/42) . feasibility . (17/42) .. / (pleurectomy/decortication: P/D) P/D . EPP . P/D . P/D EPP .. CDDP+PEM EPP . CDDP+PEM . P/D PEM . II P/D vs EPP .. P/D JMRC-01 .. EPP P/D II . P/D feasibility study .. (feasibility study) P/D .. 2) P/D . ( ) I-III (T1-3, N0-2, M0) . 75 PS(ECOG)0-1 CDDP (75mg/m2)+PEM (500mg/m2) . 3 P/D . PEM (500mg/m2) . P/D .. ( ) . 3) .. JMRC-01 17 .. 19 . 3.. JMRC-01 .. P/D . P/D feasibility . P/D vs EPP II . 4.. ( IRB) . ( IRB).. 5.. 1) Weder W, Nakano T, et al. The MARS feasibility trial: conclusions not supported by data. Lancet Oncol. 2011;12:1093-1094. 2) Maeda R, Nakano T, et al. Is serum thioredoxin-1 a useful clinical marker for malignant pleural mesothelioma? Antioxid Redox Signal, 5;685-689, 2011.

研究課題名：切除可能悪性胸膜中皮腫に対する集学的治療法の確立に関する研究 課題番号：h23―がん臨床― 一般―010

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