Transcription of EPREX INTRAVENOUS & SUBCUTANEOUS INJECTION
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EPREX INTRAVENOUS & SUBCUTANEOUS INJECTION
1 EPREX (140701) DPIEPREX INTRAVENOUS & SUBCUTANEOUS INJECTION PRODUCT INFORMATION NAME OF THE MEDICINE epoetin alfa (rch) Its CAS Registry Number is 113427-24-0. Most common abbreviation: r-HuEPO Pharmacotherapeutic group: Anti -anaemic, ATC code: B03XA01. DESCRIPTION epoetin alfa is recombinant human erythropoietin (EPO). It is expressed in Chinese hamster ovary cells (rch) and has a 165 amino acid sequence identical to that of human urinary EPO; the two are indistinguishable on the basis of functional assays. The apparent molecular weight of erythropoietin is about 30,400 daltons. EPREX pre-filled syringes contain glycine, polysorbate 80, sodium chloride, sodium phosphate dibasic dihydrate, sodium phosphate monobasic, sodium citrate and water for injections. Pharmacology Erythropoietin (EPO) is a glycoprotein hormone produced primarily by the kidney in response to hypoxia and is the key regulator of red blood cell (RBC) production.
1 EPREX(140701) DPI EPREX INTRAVENOUS & SUBCUTANEOUS INJECTION . PRODUCT INFORMATION. NAME OF THE MEDICINE . Epoetin alfa (rch) Its CAS Registry Number is 113427-24-0.
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