ERAXIS - pfizer.com.tw

(1A2 2B6 2C9 2C19 2D6 3A) 10 (8) 10 (8) . (14C) anidulafungin anidulafungin 34 (26) 48 (38) ERAXIS ( ) 8 (6) 5 (4) ERAXIS (anidulafungin) . 30% 9 12 (9) 21 (17) ERAXIS ( 34 (26) 36 (29) ERAXIS (anidulafungin) . 10% 1% Cyclosporine (CYP3A4 ) 12 11 (8) 16 (13) ) 12 (9) 20 (16) Anidulafungin . 100 Anidulafungin 6 . 8 . anidulafungin 200 100. / ( 1-8 ) cyclosporine 245 ( ERAXIS 127 fluconazole 118 ) MITT . 219 ( ERAXIS 116 fluconazole ERAXIS ( . ) .. 8 (6). 7 (5). 1 (1). 6 (5). Child-Pugh A B C . anidulafungin . ERAXIS 100 100 .. ERAXIS for Injection 100mg .. / ( 5-8 ) anidulafungin Cmax . cyclosporine anidulafungin AUC . 103 ) . (78%) . ( ) . ERAXIS / ( .. 30 (23). 7 (5). 32 (26). 10 (8). anidulafungin . Child-Pugh C AUC .. ERAXIS 2-8 C (36-46 F) . (anidulafungin) . ( 107 118 . 22% anidulafungin cyclosporine ( ).))

意識混亂狀態 患者與較年輕之患者的治療反應有任何差異，但不能排除有些10 (8) 10 (8) 憂鬱 8 (6) 5 (4)

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