Transcription of Exploring Alcohol’s Effects on Liver Function
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Exploring Alcohol’s Effects on Liver Function
N association between Liver disease and heavy alcoholconsumption was recognizedmore than 200 years ago (Smart andMann 1992). Long-term heavy alco-hol use is the most prevalent singlecause of illness and death from liverdisease in the United States (NationalCenter for Health Statistics 1994).The Liver is particularly susceptible toalcohol-related injury because it is theprimary site of alcohol alcohol is broken down in theliver, a number of potentially danger-ous by-products are generated, such asacetaldehyde and highly reactivemolecules called free radicals. Per-haps more so than alcohol itself, theseproducts contribute to alcohol-inducedliver Liver is one of the largest or-gans in the body; it has not only con-siderable reserves but also the abilityto regenerate itself. Consequently,symptoms of Liver damage may notappear until damage to the organ isquite extensive.
the effects of free radicals, antioxi-dants, and hypoxia. Free Radicals. Much of the direct cell damage that occurs during alcoholic liver disease is believed to be caused by free radicals. Free radicals are highly reactive molecular fragments that frequently contain oxygen. Small quantities of free radicals are pro-duced as normal by-products ...
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