Transcription of Exploring Alcohol’s Effects on Liver Function
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Exploring Alcohol’s Effects on Liver Function
N association between Liver disease and heavy alcoholconsumption was recognizedmore than 200 years ago (Smart andMann 1992). Long-term heavy alco-hol use is the most prevalent singlecause of illness and death from liverdisease in the United States (NationalCenter for Health Statistics 1994).The Liver is particularly susceptible toalcohol-related injury because it is theprimary site of alcohol alcohol is broken down in theliver, a number of potentially danger-ous by-products are generated, such asacetaldehyde and highly reactivemolecules called free radicals. Per-haps more so than alcohol itself, theseproducts contribute to alcohol-inducedliver Liver is one of the largest or-gans in the body; it has not only con-siderable reserves but also the abilityto regenerate itself. Consequently,symptoms of Liver damage may notappear until damage to the organ isquite extensive.
crossroads of the body, the liver filters circulating blood, removing and destroying toxic substances. It secretes bile into the small intes-THE LIVER— STRUCTURE AND FUNCTION tine to help digest fats and render them soluble for absorption. Nutrients are carried from the small intestine through the portal vein directly to the
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