Transcription of Exploring Alcohol’s Effects on Liver Function
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Exploring Alcohol’s Effects on Liver Function
N association between Liver disease and heavy alcoholconsumption was recognizedmore than 200 years ago (Smart andMann 1992). Long-term heavy alco-hol use is the most prevalent singlecause of illness and death from liverdisease in the United States (NationalCenter for Health Statistics 1994).The Liver is particularly susceptible toalcohol-related injury because it is theprimary site of alcohol alcohol is broken down in theliver, a number of potentially danger-ous by-products are generated, such asacetaldehyde and highly reactivemolecules called free radicals. Per-haps more so than alcohol itself, theseproducts contribute to alcohol-inducedliver Liver is one of the largest or-gans in the body; it has not only con-siderable reserves but also the abilityto regenerate itself.
Alcohol-related liver damage can be divided into three categories (French et al. 1993): • Fatty liver. Some degree of fat depo-sition in the liver occurs in almost all heavy drinkers. It also may occur transiently in nonalcoholics after a single drinking session. Fatty liver is reversible and is not believed to lead to more serious damage.
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