Transcription of f 2014 ン 2 - prion.umin.jp
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2014 .. 2014 . 1. 2002 1. 2008. 2014 2. i H24 12. H25 1. H25 3. H25 4. H24 3. H24 4. H25 3. H25 4. MRI. H23 9. H23 10. SSPE. H24 8. H24 9. H25 3. H25 3. H25 4. PML. H24 3. ii H24 4. - H25 3. H25 4. iii iv i ii iii iv 1. 3. 7. 7. 11. 18. 18. 21. 25. 25. 28. 32. 34. 38. 39. 41. 2. 2014 . 23 7 11. 23. 24 1 16. 1. Minds 2007.. Minds 2007. 2007.. prion transmissible spongiform encephalopathies: TSE. PrP. 1. PrP cellular prion protein: PrPC 20. PrPC 253 22. 230 GPI 181 197. 51 91 8 PrPC. scrapie prion protein: PrPSc * PrPC PrPSc PrP. Sc PrP PrPC PrPSc PrPSc PrPSc PrP 129 219. * "variably protease-sensitive prionopathy" VPSPr Zou WQ et al. Ann Neurol 2010;. 68:162-172. A. scrapie bovine spongiform encephalopathy: BSE. chronic wasting disease: CWD. B. Creutzfeldt-Jakob CJD. "Variably protease-sensitive prionopathy" VPSPr *.
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