Transcription of Factor Analysis Example - Harvard University
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Factor Analysis Example - Harvard University
Factor Analysis Example Qian-Li Xue Biostatistics Program Harvard Catalyst | The Harvard Clinical & Translational Science Center Short course, October 28, 2016 1 Example : Frailty Frailty is a biologic syndrome of decreased reserve and resistance to stressors, resulting from cumulative declines across multiple physiologic systems, and causing vulnerability to adverse outcomes (Fried et al. 2001) Common phenotypes of frailty in geriatrics include weakness, fatigue, weight loss, decreased balance, low levels of physical activity, slowed motor processing and performance, social withdrawal, mild cognitive changes, and increased vulnerability to stressors (Walston et al.)
Use Principal Components Analysis (PCA) to help decide ! Similar to “factor” analysis, but conceptually quite different! ! number of “factors” is equivalent to number of variables ! each “factor” or principal component is a weighted combination of the input variables Y 1 …. Y n: P 1 = a 11Y 1 + a 12Y 2 + …. a 1nY n
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