Fatty Acid Biosynthesis
by malic enzyme • Pyruvate translocase transports pyruvate into mitochondria. • Pyruvate is converted to oxaloacetate by pyruvate carboxylase with coupled hydrolysis of one ATP. Pyruvate + ATP + CO2 + H2O Æ oxaloacetate + ADP + Pi (reaction of gluconeogenesis) • Net Reaction: NADP+ + NADH + H+ + ATP + H 2O ÆNADPH + NAD+ + ADP + Pi
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