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Fatty Acids: Structures and Introductory article Properties

Fatty Acids: Structures andPropertiesArild C Rustan,University of Oslo, Oslo, NorwayChristian A Drevon,University of Oslo, Oslo, NorwayFatty acids play a key role in metabolism: as a metabolic fuel, as a necessary component ofall membranes, and as a gene regulator. In addition, Fatty acids have a number of acids, both free and as part of complex lipids, play anumber of key roles in metabolism major metabolic fuel(storage and transport of energy), as essential componentsof all membranes, and as gene regulators (Table 1). In ad-dition, dietary lipids provide polyunsaturated Fatty acids(PUFAs) that are precursors of powerful locally actingmetabolites, the eicosanoids.

fatty acid depends on whether the chain is even- or odd-numbered; the latter have higher melting points. Saturated fatty acids are very stable, whereas unsatu-rated acids are susceptible to oxidation: the more double ATP formation and heat dissipation Glucose Glucose FFA Acyl-CoA ACBP Peroxisome FABP Albumin Mitochondrion Esterification ...

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