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Filter Housing Heaters: Electrical Versus Steam

ManufacturingVent filters are critical to the safe and sterile operationof chemical reaction and storage vessels in thebiopharmaceutical industry. Normally, a vent Filter isoperational during the introduction of sterile air ornitrogen during and after vessel sterilisation, as well asduring other routine operations such as venting the gasin a vessel while it is being filled. The upstream side ofthe vent Filter constitutes one boundary of the sterileoperation envelope of the reactor system. Clean in place (CIP) procedures are commonly usedin the biopharmaceutical industry to clean andsterilise reaction vessels, and most CIP routinesemploy Steam sterilisation of the vessel as a finalstep.

the filter housing. Also, biopharmaceutical plants typically have steam available throughout the plant site. Safety interlocks based on the steam

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