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FINAL CLINICAL STUDY REPORT

MAPS CLINICAL STUDY REPORT MP-2 15-SEP-2011 Page 1 of 62 FINAL CLINICAL STUDY REPORT Protocol #: MP- 2 IND #: 63,384 September 15, 2011 First Subject First Visit: July 18, 2006 Last Subject Last Visit: January 10, 2011 Phase Two Pilot STUDY : 3,4-methylenedioxymethamphetamine (MDMA)-assisted Psychotherapy in Patients with Treatment-resistant Posttraumatic Stress Disorder (PTSD) A randomized, single-center, active placebo-controlled, double-blind, partial crossover STUDY comparing response to psychotherapy assisted by 25mg or 125 mg MDMA. A STUDY performed in accordance with the principles of Good CLINICAL Practice as described in International Conference of Harmonization guidelines, including the archiving of essential documents.

MAPS Clinical Study Report MP-2 15-SEP-2011 MP-2_CSR_FINAL_15SEP11.pdf Page 1 of 62 FINAL CLINICAL STUDY REPORT Protocol #: MP- 2 IND #: 63,384

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