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Instructions:The goal of this template is to help you focus your aims, one vital component of writing a successful proposal. This template is derived directly from R01 s of mine that were funded with scores better than the 5th percentile, and it has also been used by various people I ve helped, several of whom have used it to score in the top few percentile. Bottom line is, when you combine this with some of the other aspects of a great grant ( great team, great project, etc), this approach aims are a crucial part of winning over the reviewer. Your whole proposal should be written for a general science audience, not for just specialists in your field.

top-down and bottom-up mass spectrometry data, we will enhance our PROCLAME software to use a Markov chain Monte Carlo algorithm that can incorporate: a) intact-mass mass data from top-down analysis, b) peptide data from bottom-up analysis, and c) context-sensitive rules that use but are not limited by knowledge of where modifications are

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