Transcription of FOR INTRAVENOUS USE ONLY
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FOR INTRAVENOUS USE ONLY
NDA 50-706/S-022 Page 3 MERREM (meropenem for injection) FOR INTRAVENOUS USE ONLY To reduce the development of drug-resistant bacteria and maintain the effectiveness of MERREM (meropenem for injection) and other antibacterial drugs, MERREM should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION MERREM (meropenem for injection) is a sterile, pyrogen-free, synthetic, broad-spectrum, carbapenem antibiotic for INTRAVENOUS administration. It is (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbam oyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydr oxyethyl]-4-methyl-7-oxo-1-azabicyclo[ ]hept-2-ene-2-carboxylic acid trihydrate.
SUSCEPTIBILITY TEST METHODS When available, the clinical microbiology laboratory should provide cumulative results of in vitro susceptibility test results for antimicrobial drugs used in local hospitals and practice areas to the physician as periodic reports that describe the susceptibility profile of nosocomial and community-acquired pathogens.
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