General Pathology Notes - BU

General Pathology Lecture Notes INTRODUCTION TO Pathology Introduction to Pathology General Pathology is the study of the mechanisms of disease (with emphasis on aetiology and pathogenesis), while systematic Pathology is the study of diseases as they occur within particular organ systems it involves aetiology, pathogenesis, epidemiology, macro- and microscopic appearance, specific diagnostic features, natural history and sequelae. Academic Pathology includes research and teaching, and the discipline of experimental Pathology was derived from this. Clinical Pathology is often referred to as laboratory medicine and includes a number of diagnostic disciplines. Pathology provides the basis for understanding: The mechanisms of disease The classification of diseases The diagnosis of diseases The basis of treatment Monitoring the progress of disease Determining

Cause of injury – ischaemic, physical, chemical, infectious, immunological Time course – rapid and acute, or slow and chronic (depends on the pathogenic mechanism, persistence of the injurous agent and presence of certain cell types) Initial reactions – localized, non-specific systemic manifestations (e.g. pyrexia)

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