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Genotoxic Impurities and Its Risk Assessment in Drug …

Citation: Amit G, Hussain S, Tabrez S. Genotoxic Impurities and Its Risk Assessment in Drug Compounds. Drug Des Int Prop Int J 2(4). DOI: Impurities and Its Risk Assessment in Drug CompoundsAmit Gosar1, Hussain Sayyed2 and Tabrez Shaikh3*1,3 Indoco Research Centre, Navimumbai, Maharashtra, India2,3 Sir Sayyed College, Department of Chemistry, Aurangabad, IndiaReceived: October 17, 2018; Published: October 23, 2018*Corresponding author: Tabrez Shaikh, Indoco Research Centre, Rabale, Navi Mumbai, Maharashtra, India UPINE PUBLISHERS Open AccessLDrug Designing & Intellectual Properties International JournalReview ArticleIntroductionPharmaceutical drugs are always associated with some unwanted chemicals along with active components.

Genotoxic impurities can get incorporated into drug substances through the various sources, the major source is the starting material used in the synthesis of drug substances and its impurities. Similarly, genotoxic intermediate and by-products formed in the

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accelerate.ucsf.edu

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