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GUIDELINES

GUIDELINESV ersion 2019 EnglishGUIDELINESV ersion 2021 EnglishEACS EuropeanAIDS Clinical Society1 EACS GUIDELINES of Contents Introduction to EACS GUIDELINES 20213 Summary of Changes from to Members5 Governing Board Members5 Abbreviations6 Part IAssessment of PLWH at Initial & Subsequent Visits7 Part IIART of PLWH10 Assessing PLWH's Readiness to Start and Maintain ART 10 Recommendations for Initiation of ART in PLWH with Chronic Infection without prior ART Exposure 12 Initial Combination Regimen for ART-na ve Adult PLWH 13 Primary HIV Infection (PHI)15 Switch Strategies for Virologically Suppressed Persons16 Virological Failure17 treatment of Pregnant Women Living with HIV or Women Considering Pregnancy18 ART in TB/HIV Co-infection20 Post-exposure Prophylaxis (PEP) 22 Pre-exposure Prophylaxis (PrEP)23 Adverse Effects of ARVs and Drug Classes 24 Part IIIDrug-drug Interactions and

Opportunistic Infections and COVID-19 123 When to start ART in PLWH with Opportunistic Infections (OIs) 123 Immune Reconstitution Inflammatory Syndrome (IRIS) 124 Primary Prophylaxis of OIs According to Stage of Immunodeficiency 125 Primary Prophylaxis, Treatment and Secondary Prophylaxis/ Maintenance Treatment of Individual OIs 126

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